Case Session 01: Ischemic Heart Disease and Acute Chest Pain (2018)-T1 mapping detect distal bed matrix changes in coronary artery lesions’ configuration changes in developing ischemia, a case report

T1 mapping detect distal bed matrix changes in coronary artery lesions’ configuration changes in developing ischemia, a case report

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Video Transcription

Video Summary

The speaker presents cases showing that T1 and T2 mapping on cardiac MRI can detect early myocardial “matrix changes” linked to coronary artery disease, even when stress MRI, late enhancement, FFR, or angiography appear negative or non-significant. In one patient, T1 mapping matched a newly significant LAD lesion that had been mild a year earlier. In another, MRI revealed edema and matrix change despite negative functional tests. The speaker suggests these findings may reflect early disease progression or microembolization and asks whether such patients should receive intervention or medical therapy.

Keywords

cardiac MRI

T1 mapping

T2 mapping

coronary artery disease

myocardial matrix changes