Case Session 02: Non-ischemic Cardiomyopathies (2018)-Diagnostic biopsy and regenerative therapy with real-time MR guidance

Diagnostic biopsy and regenerative therapy with real-time MR guidance

Video Transcription

Video Summary

The speaker discussed real-time MRI guidance in interventional cardiology, focusing on regenerative therapies for ischemic heart disease. MRI offers precise anatomical and functional imaging, better biopsy yields, no radiation, and improved targeting of infarct border zones. A consortium developed an MRI-guided injection strategy using active and passive catheter tracking plus an MRI-compatible, steerable, trackable injection catheter. In pig studies, they successfully navigated to the left ventricle and delivered MRI-visible hydrogel into target areas. The approach aims to improve cell retention and treatment accuracy, with future work needed on workflow, sequence optimization, and MRI-compatible transseptal access.

Keywords

real-time MRI guidance

interventional cardiology

regenerative therapies

ischemic heart disease

MRI-guided injection catheter