Invited Lecture Session 01: Normal Ranges and Standardized Protocols-clip-20170216032055

Video Transcription

Video Summary

The talk focused on standardizing cardiac parametric mapping, especially native T1, T2, ECV, and some T2*. The speaker described how these biomarkers have moved from technical development to early clinical use and now into larger trials, with the goal of improving patient outcomes and supporting therapy decisions. A key theme was that mapping measures water properties in tissue, making it possible to detect disease processes like edema, amyloid, myocarditis, and diffuse fibrosis without biopsy.  <br /><br />Standardization matters most for subtle, low-signal diseases such as diffuse fibrosis, where small technical drift can greatly affect diagnosis and treatment decisions. The speaker emphasized the need to define normal values carefully, control biological and technical variability, and use phantoms to monitor scanner stability across sites. Large multicenter efforts suggest MRI systems are fairly stable, and upcoming consensus recommendations should guide scanning protocols, hardware setup, and quality control.

Keywords

cardiac parametric mapping

native T1 T2 ECV

myocardial tissue characterization

standardization and quality control

diffuse fibrosis