Oral Abstract Session 01: Early Career Awards 1: Clinical (2018)-Combined high-resolution stress perfusion and scar assessment in patients with ischaemic cardiomyopathy

Combined high-resolution stress perfusion and scar assessment in patients with ischaemic cardiomyopathy

Video Transcription

Video Summary

The speaker discusses cardiac MRI for ischemic heart failure, emphasizing that visual assessment can underestimate ischemia while standard segmental quantification may overestimate it by ignoring scar. To address this, the team developed a high-resolution fusion method combining stress perfusion and late gadolinium enhancement, preserving both ischemia and scar information. In 161 patients with severe coronary disease and reduced ejection fraction, this approach more accurately measured “true ischemic burden,” improved vessel-level assessment, and identified more three-vessel disease than visual analysis. The conclusion: integrated high-resolution quantification better guides treatment by accounting for overlap between scar and ischemia.

Keywords

cardiac MRI

ischemic heart failure

stress perfusion

late gadolinium enhancement

ischemic burden