Oral Abstract Session 02: Early Career Awards 2: Translational (2018)-Validation of myocardial perfusion mapping: from invasive physiology to mapping

Validation of myocardial perfusion mapping: from invasive physiology to mapping

Video Transcription

Video Summary

The speaker presented a study validating CMR myocardial perfusion mapping against invasive coronary physiology in patients with angina. In 36 patients, stress myocardial blood flow and perfusion reserve were lower in vessels with abnormal FFR, showing good sensitivity for epicardial disease. The technique also detected microvascular dysfunction, identified by elevated IMR, even when FFR was normal. Perfusion mapping may help distinguish epicardial stenosis, microvascular dysfunction, and normal vessels, potentially guiding who needs angiography or can be safely discharged. Further validation is needed before routine clinical use.

Keywords

CMR myocardial perfusion mapping

fractional flow reserve

microvascular dysfunction

coronary physiology

angina diagnosis