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Plenary 2: CMR Quantification in Clincal Research ...
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The speaker argues that both qualitative and quantitative MRI approaches are valuable, but they serve different purposes. Qualitative interpretation is fast, practical, trainable, and often sufficient for clear-cut diagnoses or immediate clinical decisions. However, it can be subjective and biased, and may miss complex, continuous disease processes. Quantitative MRI is more objective, reproducible, and generalizable, making it essential for research and for detecting subtle physiology that visual assessment can overlook, such as multivessel disease or microvascular ischemia. Quantification also improves sample-size calculations, trial efficiency, and cost by reducing measurement variability, especially with paired, subject-based study designs. Overall, the speaker concludes that quantitative CMR should be the backbone of both research and clinical practice because it improves qualitative judgment and ultimately leads to better patient care.
Keywords
qualitative MRI
quantitative MRI
cardiac MRI
clinical decision-making
microvascular ischemia
research reproducibility
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