Scientific Abstracts - Pediatric and Congenital Heart Disease Scientific Presentations-Noninvasive quantification of pressure-volume loops in patients with atrial septal defect at rest and stress

Noninvasive quantification of pressure-volume loops in patients with atrial septal defect at rest and stress

Video Transcription

Video Summary

This study used a noninvasive method to derive left ventricular pressure-volume loops from cardiac MRI and brachial pressure in patients with atrial septal defect (ASD) and healthy controls at rest and stress. Eighteen ASD patients and 60 controls were studied. Compared with controls, ASD patients had lower stroke work and external power at rest, and unlike controls, they did not increase stroke work during stress. Potential energy fell with stress in both groups, while ventricular efficiency and energy per ejected volume were similar. The method may help assess left ventricular hemodynamics without invasive catheterization.

Keywords

atrial septal defect

left ventricular pressure-volume loops

cardiac MRI

ventricular hemodynamics

stroke work