Technical - Emerging CMR Methods - Acquisition & Reconstruction-Quantitative assessment of Simultaneous Multi Slice balanced steady state free precession (SMS-bSSFP) dual bolus first pass pulmonary perfusion imaging in pulmonary hypertension

Quantitative assessment of Simultaneous Multi Slice balanced steady state free precession (SMS-bSSFP) dual bolus first pass pulmonary perfusion imaging in pulmonary hypertension

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This study evaluated a dual-bolus, simultaneous multi-slice cardiac MRI perfusion sequence for pulmonary hypertension assessment. In 12 patients, 16 lung slices were acquired every 2 seconds on a 1.5T scanner, and automated pixel-wise analysis measured pulmonary blood flow and blood volume. Quantitative perfusion maps matched visual interpretation and clinical diagnosis, distinguishing normal subjects, pulmonary hypertension, and chronic thromboembolic pulmonary hypertension. A flow cutoff of 2.71 mL/min showed high diagnostic accuracy. The authors conclude that this radiation-free MRI technique is feasible, accurate, and promising for noninvasive screening, diagnosis, and follow-up of pulmonary hypertension.

Keywords

cardiac MRI perfusion

pulmonary hypertension

simultaneous multi-slice

pulmonary blood flow

noninvasive screening