Technical - Emerging CMR Methods - Tissue Characterization-Endogenous assessment of myocardial injury with single-shot non-rigid motion-corrected adiabatic T1 rho mapping

Endogenous assessment of myocardial injury with single-shot non-rigid motion-corrected adiabatic T1 rho mapping

Video Transcription

Video Summary

The speaker presented a contrast-free cardiac MRI framework for myocardial injury assessment using single-shot, breath-held, ECG-triggered T1rho mapping with non-rigid motion correction. The method was fully integrated into a 1.5T scanner and tested in healthy volunteers and 30 patients. Motion correction improved image quality and reduced cardiac/respiratory artifacts, enabling clearer visualization of injured myocardium. In patients, T1rho elevations corresponded well with late gadolinium enhancement findings, with reported sensitivity of 93% and specificity of 89%. The study suggests T1rho mapping may become a practical tool for detecting myocardial fibrosis and injury without contrast agents.

Keywords

cardiac MRI

T1rho mapping

myocardial injury

motion correction

contrast-free imaging