Techniques and Methods Session 4: Rethinking Imaging of Function, Flow, Perfusion, and Morphology (2020)-Multicenter study shows that valvular 4D-flow MRI is internationally clinical acceptable

Multicenter study shows that valvular 4D-flow MRI is internationally clinical acceptable

Video Transcription

Video Summary

This multicenter study evaluated automated retrospective valve tracking in flow MRI to quantify regurgitation and forward flow across four heart valves. Six international sites analyzed 20 subjects each, using varied scanners and protocols, while a central reader repeated the measurements. The study compared inter-observer and inter-site agreement using Bland-Altman analysis, ICC, and coefficient of variation. Results showed strong agreement for net forward volume, regurgitation fraction, and net forward variation. Despite technical differences between centers, measurements were clinically acceptable in over 75% of cases, with a target threshold of under 10% variation.

Keywords

flow MRI

valve tracking

regurgitation fraction

inter-site agreement

Bland-Altman analysis