Technologist Track Session 01: CMR Technical Methods (2018)-T1/T2 parametric mapping

Video Transcription

Video Summary

The speaker explains cardiac MRI tissue characterization, starting with late gadolinium enhancement (LGE). LGE is useful for detecting myocardial damage, but diffuse enhancement can be misleading if inversion time is not set correctly. Because LGE cannot quantify diffuse fibrosis well, T1 and T2 mapping are presented as better solutions.  <br /><br />For T1 mapping, the talk compares inversion recovery and saturation recovery methods, and reviews common sequences such as conventional inversion recovery, Look-Locker, and MOLLI, along with newer variants like modified MOLLI, ShMOLLI, SASHA, and SMART1. Key trade-offs include scan time, heart-rate sensitivity, accuracy, and precision. The speaker also notes the importance of fitting methods, motion correction, and calculating extracellular volume.  <br /><br />T2 mapping is then briefly covered, mainly using T2-prepared imaging and multi-echo spin echo methods, each with specific limitations. The presentation ends by recommending a review article on these techniques.

Keywords

cardiac MRI

late gadolinium enhancement

T1 mapping

T2 mapping

myocardial fibrosis